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Contact information |
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Education/experience
Postdoc, Washington University in St Louis, Department of Biochemistry and Molecular Biophysics (2019–2022)
PhD, Physics, Concordia University (2019)
MSc, Computational Sciences and Engineering, Koç University (2014)
BSc, Istanbul Technical University, Physics Engineering (2011)
Research
I use computational modeling to study the within-membrane assembly of membrane proteins. I'm also interested in studying how lipids modulate function, conformational dynamics and association of these proteins. Biophysics education is an additional interest of mine.
Publications
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[14] TN Ozturk, M Konig, TS Carpenter ,KB Pedersen, TA Wassenaar, HI Ingólfsson, SJ Marrink (2024). Building complex membranes with Martini 3 (in revision, Methods in Enzymology) |
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[13] L Borges-Araújo, A Borges-Araújo, TN Ozturk, DP Ramirez-Echemendia, B Fábián, TS Carpenter, S Thallmair, J Barnoud, HI Ingólfsson, G Hummer, DP Tieleman, SJ Marrink, PCT Souza, MN Melo. (2023). Martini 3 Coarse-Grained Force Field for Cholesterol. Journal of Chemical Theory and Computation, 19(20), 7387-7404 |
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[12] TN Ozturk*, N Bernhardt*, N Schwartz, R Chadda, JL Robertson and JD Faraldo-Gomez. (2023). Mitigation of membrane morphology defects explain stability and orientational specificity of CLC dimers, BioRxiv, DOI: 10.1101/2023.03.16.533024 |
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[11] M Ernst, TN Ozturk, JL Robertson. (2023). A single-molecule method for measuring fluorophore labeling yields for the study of membrane protein oligomerization in membranes. PloS one 18(1), e0280693 |
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[10] TN Ozturk, C. Coumoundouros, D. Culham and J. Wood. (2023). Structural determinants and functional significance of dimerization for osmosensing transporter ProP in Escherichia coli. Biochemistry 62(1) 118-133 |
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[9] S Ahrari, TN Ozturk, N D’Avanzo. (2022). Ion behaviour in the selectivity filter of HCN1 channels. Biophysical Journal 121 (11), 2206-2218 |
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[8] EA Orabi, TN Öztürk, N Bernhardt, JD Faraldo-Gómez. (2021). Corrections in the CHARMM36 Parametrization of Chloride Interactions with Proteins, Lipids, and Alkali Cations, and Extension to Other Halide Anions. Journal of Chemical Theory and Computation 17 (10), 6240-6261 |
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[7] K Mersch, TN Ozturk, K Park, HH Lim, JL Robertson. (2021). Altering CLC stoichiometry by reducing non-polar side-chains at the dimerization interface. Journal of Molecular Biology 433 (8), 166886 |
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[6] R Chadda, N Bernhardt, EG Kelley, SC Teixeira, K Griffith, A Gil-Ley, TN Öztürk, LE Hughes, A Forsythe, V Krishnamani, JD Faraldo-Gómez, JL Robertson. (2021). Membrane transporter dimerization driven by differential lipid solvation energetics of dissociated and associated states. Elife 10, e63288 |
| [5] TN Ozturk, DE Culham, L Tempelhagen, JM Wood, G Lamoureux. (2020). Salt-Dependent Interactions between the C-Terminal Domain of Osmoregulatory Transporter ProP of Escherichia coli and the Lipid Membrane. The Journal of Physical Chemistry B 124 (38), 8209–8220 |
| [4] L Krohn*, TN Öztürk*, B Vanderperre*, B Ouled Amar Bencheikh, JA Ruskey, … (2020). Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies. Annals of Neurology 87 (1), 139–153 |
| [3] DE Culham, D Marom, R Boutin, J Garner, TN Ozturk, N Sahtout, L Tempelhagen, G Lamoureux, and JM Wood (2018). Dual role of the C-terminal domain in osmosensing by bacterial osmolyte transporter ProP. Biophysical Journal 115 (11), 2152–2166 |
| [2] TN Ozturk, S Keskin. (2014). Computational screening of porous coordination networks for adsorption and membrane-based gas separations. The Journal of Physical Chemistry C 118 (25), 13988–13997 |
| [1] TN Ozturk, S Keskin. (2013). Predicting gas separation performances of porous coordination networks using atomistic simulations. Industrial & Engineering Chemistry Research 52 (49), 17627–17639 |